Abstract
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Abstract
Outlines how excessive levels of opioids in the central nervous system (CNS) affect and modify the classical neurotransmission systems and result in some of the perceptual, social, and behavioral difficulties that define autism. Preliminary results of urinary peptide analysis, by high-pressure liquid chromatography, showed marked differences between 25 autistic and 20 normal Ss (aged 18–50 yrs). Most Ss with the fragile-X-chromosomal abnormality had a similar, characteristic but distinct peptide abnormality as did a smaller subgroup of Ss with Down’s syndrome and nonspecific mental handicaps.”
- January 1, 1990
