Pertussis vaccine

A suspension of killed Bordetella pertussis organisms, used for immunization against pertussis (WHOOPING COUGH). It is generally used in a mixture with diphtheria and tetanus toxoids (DTP). There is an acellular pertussis vaccine prepared from the purified antigenic components of Bordetella pertussis, which causes fewer adverse reactions than whole-cell vaccine and, like the whole-cell vaccine, is generally used in a mixture with diphtheria and tetanus toxoids. – NLM Medical Subject Headings U.S. National Library of Medicine

No study has examined the relationship between the pertussis vaccine and autism causation, despite parental reports of regressions into autism following the pertussis vaccine.

Pertussis vaccine is associated with higher all cause mortality.

Autoimmunity / DTaP / Males / Pertussis vaccine / Pregnancy / Preterm / Unvaccinated / Vaccine Schedule

Pilot comparative study on the health of vaccinated and unvaccinated 6- to 12- year old U.S. childrend

Excerpts:
“NDD, a derived diagnostic measure, was defined as having one or more of the following three closely-related diagnoses: a learning disability, Attention Deficient Hyperactivity Disorder, and Autism Spectrum Disorder.”

“Vaccinated children were significantly more likely than the unvaccinated to have been diagnosed with the following… ASD (4.7% vs. 1.0%, p = 0.013; OR 4.2, 95% CI: 1.2, 14.5),”

“In conclusion, vaccinated homeschool children were found to have a higher rate of allergies and NDD than unvaccinated homeschool children.”

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  • April 24, 2017
Adjuvant / DTaP / Hypotonia / Mercury / MMR / Pertussis vaccine / Seizure / Thimerosal / Toxicants / Vaccine adverse events

Neurological adverse events associated with vaccination

Abstract

Public tolerance to adverse reactions is minimal. Several reporting systems have been established to monitor adverse events following immunization. The present review summarizes data on neurologic complications following vaccination, and provides evidence that indicates whether they were directly associated with the vaccines. These complications include autism (measles vaccine), multiple sclerosis (hepatitis B vaccine), meningoencephalitis (Japanese encephalitis vaccine), Guillain-Barré syndrome and giant cell arteritis (influenza vaccine), and reactions after exposure to animal rabies vaccine. Seizures and hypotonic/hyporesponsive episodes following pertussis vaccination and potential risks associated with varicella vaccination, as well as vaccine-associated paralytic poliomyelitis following oral poliovirus vaccination, are also described. In addition, claims that complications are caused by adjuvants, preservatives and contaminants [i.e. macrophagic myofasciitis (aluminium), neurotoxicity (thimerosal), and new variant Creutzfeldt-Jakob disease (bovine-derived materials)] are discussed.

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  • June 7, 2002
Pertussis vaccine

Adverse Effects of Pertussis and Rubella Vaccines: A Report of the Committee to Review the Adverse Consequences of Pertussis and Rubella Vaccines

Excerpt:
“In November 1989, IOM established the Committee to Review the Adverse Consequences of Pertussis and Rubella Vaccines. The specific charge to the committee, as outlined in Section 312 of the National Childhood Vaccine Injury Act, was to: identify and review all available medical and scientific literature on the nature, circumstance, and extent of the relationship, if any, between vaccines containing pertussis (including whole cells, extracts, and specific antigens) and the following illnesses and conditions: hemolytic anemia, hypsarrhythmia, infantile spasms, Reye syndrome, peripheral mononeuropathy, deaths classified as sudden infant death syndrome (SIDS), aseptic meningitis, juvenile diabetes, autism, learning disabilities, hyperactivity, and other such illnesses as recommended by the committee or the Advisory Commission on Childhood Vaccines”

“Summary

No data were identified that address the question of a relation between vaccination with DPT or its pertussis component and autism. There are no experimental data bearing on a possible biologic mechanism.
Conclusion

There is no evidence to indicate a causal relation between DPT vaccine or the pertussis component of DPT vaccine and autism.”

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  • January 1, 1991

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