Autistic disorder in 2 children with mitochondrial disorders

J Child Neurol. 2007 Sep;22(9):1121-3. doi: 10.1177/0883073807306266.

Autistic disorder in 2 children with mitochondrial disorders

Chang-Yong Tsao 1 , Jerry R Mendell

1 Department of Pediatrics, The Ohio State University, Columbus, Ohio, USA. tsaoc@pediatrics.ohio-state.edu

Abstract

Autistic disorder is a heterogeneous disorder. The majority of the cases are idiopathic, and only a small number of the autistic children have associated secondary diagnosis. This article reports 2 children with mitochondrial disorders associated with autistic disorder fulfilling the diagnostic criteria of the American Psychiatric Association Manual of Psychiatric Diseases, 4th edition, and briefly reviews the literature on autistic disorder associated with mitochondrial disorders.