Profile of autism spectrum disorders in Morocco: cross-sectional retrospective study of parents of children with autism
Med Pharm Rep. 2023 Jan;96(1):71-78. doi: 10.15386/mpr-2308. Epub 2023 Jan 25.
Mohamed Réda Sefrioui 1 , Imane Elidrissi 2 , Ibrahim Sbai El Othmani 1 , Sanae Derfoufi 1 , Amal Ait Haj Said 1 , Adnane Benmoussa 1 , Soufiane Derraji 2
1 Laboratory of Drug Science, Biomedical and Biotechnological Research, Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Casablanca, Morocco.
2 Laboratory of Pharmacology-Toxicology, Faculty of Medicine and Pharmacy, Mohamed V University in Rabat, Rabat, Morocco.
Abstract
Context and objective: In Morocco, autism is a frequent disorder and no epidemiological studies have been carried out. The aim of this work is to analyze the characteristics of the onset of autism in children.
Settings and design: We conducted a cross-sectional retrospective study, spread over a period of 10 months.
Methods: We included in our survey children who, according to the DSM 5 definition, had one of the autism spectrum disorders and had a well-defined diagnosis. For the statistical analysis we used Excel® software. We used the percentages for the description of the qualitative variables.
Results: Of the parents of children with ASD, 49% were biological mothers. Of these, 30% women had their child when they were between 30 and 35 years of age. Males accounted for 61% of children with a sex ratio of 2.6. The first autistic traits appeared at the age of 18 months for 22% of our population. Of mothers with children with ASD, 83% had regular medical follow-up throughout their pregnancy. All autistic children in our population were vaccinated according to the National Immunization Program. According to parent reports, 70% affirmed that the first autistic features appeared after vaccination with the measles-mumps-rubella (MMR) vaccine, knowing that this statement is not based on evidence.
Conclusions: The quality of care depends on the age at which the diagnosis of autism is established.