C-reactive protein

C-reactive protein (CRP) is a protein made by the liver. The level of CRP increases when there’s inflammation in the body. – Mayo Clinic

C-reactive protein / Inflammation / Pregnancy

Elevated maternal C-reactive protein and autism in a national birth cohort

Excerpt:
“Increasing maternal CRP levels, classified as a continuous variable, were significantly associated with autism in offspring. For maternal CRP levels in the highest quintile, compared with the lowest quintile, there was a significant, 43% elevated risk. This finding suggests that maternal inflammation may have a significant role in autism, with possible implications for identifying preventive strategies and pathogenic mechanisms in autism and other neurodevelopmental disorders.”

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  • January 22, 2013
C-reactive protein / Flu Vaccine / IL-6 / Immune / Inflammation / Pregnancy / Preterm / TNF-α

Inflammatory Responses to Trivalent Influenza Virus Vaccine Among Pregnant Women

Conclusions
Trivalent influenza virus vaccination elicits a measurable inflammatory response among pregnant women. There is sufficient variability in response for testing associations with clinical outcomes. As adverse perinatal health outcomes including preeclampsia and preterm birth have an inflammatory component, a tendency toward greater inflammatory responding to immune triggers may predict risk of adverse outcomes, providing insight into biological mechanisms underlying risk.

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  • November 8, 2011

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